Title : Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation.

Pub. Date : 1990 Sep-Oct

PMID : 2133091






1 Functional Relationships(s)
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1 Contradictory results as to the role of cytochrome P-450 mediated metabolism of acrylamide in the induction of neurotoxic effects prompted us to investigate the possible formation of glycidamide, a reactive epoxide metabolite. Acrylamide cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus