Title : Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells.

Pub. Date : 2011 Mar

PMID : 21328464






1 Functional Relationships(s)
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1 These data suggest that the delay of PGE(2) release after COX-2 upregulation triggered by PAR1 is due to the poor supply of free arachidonic acid at the early stage in RGM1 cells, and that plural isozymes of PLA(2) including sPLA(2)-IIA may complementarily contribute to the liberation of free arachidonic acid. Arachidonic Acid cytochrome c oxidase II, mitochondrial Rattus norvegicus