Pub. Date : 2011 May
PMID : 21324712
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histamine suppressed tumor necrosis factor alpha (TNF-alpha)- and interferon-gamma (IFN-gamma)-induced production of CC chemokine ligand 17(CCL17), a type 2 T-helper (Th2) chemokine, by HaCaT KCs. | Histamine | tumor necrosis factor | Homo sapiens |
| 2 | Histamine suppressed tumor necrosis factor alpha (TNF-alpha)- and interferon-gamma (IFN-gamma)-induced production of CC chemokine ligand 17(CCL17), a type 2 T-helper (Th2) chemokine, by HaCaT KCs. | Histamine | tumor necrosis factor | Homo sapiens |
| 3 | In contrast, histamine enhanced the production of CXC chemokine ligand 10 (CXCL10), a Th1 chemokine, by TNF-alpha- and IFN-gamma-stimulated HaCaT KCs and NHKs. | Histamine | tumor necrosis factor | Homo sapiens |
| 4 | TNF-alpha- and IFN-gamma-induced CXCL10 production was upregulated by suppression of p38 MAP kinase or NF-kappaB activity, which could explain histamine involvement. | Histamine | tumor necrosis factor | Homo sapiens |