Title : Akt, 14-3-3ΞΆ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma.

Pub. Date : 2011 May

PMID : 21323512






1 Functional Relationships(s)
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1 Development of resistance to the CHOP chemotherapeutic regimen (cyclophosphamide, doxorubicin, vincristine, prednisone) remains a major cause of treatment failure and mortality in approximately 40% of patients with diffuse large B-cell lymphoma (DLBCL). Cyclophosphamide DNA damage inducible transcript 3 Homo sapiens