Title : Down-regulation of μ-protocadherin expression is a common event in colorectal carcinogenesis.

Pub. Date : 2011 Jul

PMID : 21315419






1 Functional Relationships(s)
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1 We have previously reported that treatment of colorectal cancer cells with mesalazine results in the up-regulated expression of a novel member of the cadherin protein superfamily, named mu-protocadherin, which is able to sequester beta-catenin on plasmatic membrane of treated cells inhibiting its proliferation signalling pathway. Mesalamine catenin beta 1 Homo sapiens