Title : Broad-spectrum antimicrobial peptide resistance by MprF-mediated aminoacylation and flipping of phospholipids.

Pub. Date : 2011 Apr

PMID : 21306448






1 Functional Relationships(s)
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1 Intriguingly, specific point mutations in mprF cause resistance to the CAMP-like antibiotic daptomycin in a yet unclear way that may involve altered Lys-PG synthesis and/or Lys-PG flipping capacities. Daptomycin cathelicidin antimicrobial peptide Homo sapiens