Title : Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

Pub. Date : 2011 Jun

PMID : 21303699






2 Functional Relationships(s)
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1 Moreover, the incubation of cells with ammonium chloride or bafilomycin A1 to produce the lysosomal dysfunction recently reported in Parkinson"s disease led to an increase in the release of alpha-synuclein in exosomes and a concomitant increase in alpha-synuclein transmission to recipient cells. Ammonium Chloride synuclein alpha Homo sapiens
2 Moreover, the incubation of cells with ammonium chloride or bafilomycin A1 to produce the lysosomal dysfunction recently reported in Parkinson"s disease led to an increase in the release of alpha-synuclein in exosomes and a concomitant increase in alpha-synuclein transmission to recipient cells. Ammonium Chloride synuclein alpha Homo sapiens