Title : Phenethyl isothiocyanate inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory responses in mouse skin.

Pub. Date : 2011 Apr

PMID : 21303260






1 Functional Relationships(s)
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1 Topical application of 5 nmol of TPA to mouse ears markedly increased the ear weight, expression of the inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 protein, and phosphorylation of the inhibitor of kappaB (IkappaB) alpha, AKT, and extracellular signal-regulated protein kinase (ERK) 1/2 and reduced IkappaBalpha protein levels. Tetradecanoylphorbol Acetate thymoma viral proto-oncogene 1 Mus musculus