Title : Bronchial epithelium-derived IL-8 and RANTES increased bronchial smooth muscle cell migration and proliferation by Krüppel-like factor 5 in areca nut-mediated airway remodeling.

Pub. Date : 2011 May

PMID : 21297082






1 Functional Relationships(s)
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1 Induction of BSMC proliferation and migration by sANE-BEAS-2B-CM and -HBE-CM was associated with increased phosphorylation of Raf, MEK1/2, and extracellular signal regulated kinase (ERK)1/2 and the upregulation of kruppel-like factor 5 (KLF5), cyclin D, and integrin-linked kinase. bsmc zinc fingers and homeoboxes 2 Homo sapiens