Pub. Date : 2011 May 1
PMID : 21292779
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. | polyglutamine | ataxin 2 | Homo sapiens |
| 2 | We recently identified intermediate-length polyglutamine (polyQ) expansions (27-33 Qs) in ataxin 2 as a genetic risk factor for sporadic ALS in North American ALS patients. | polyglutamine | ataxin 2 | Homo sapiens |
| 3 | We recently identified intermediate-length polyglutamine (polyQ) expansions (27-33 Qs) in ataxin 2 as a genetic risk factor for sporadic ALS in North American ALS patients. | polyglutamine | ataxin 2 | Homo sapiens |
| 4 | To extend these findings, we assessed the ataxin 2 polyQ repeat length in 1294 European ALS patients and 679 matched healthy controls. | polyglutamine | ataxin 2 | Homo sapiens |
| 5 | Our findings support the hypothesis that ataxin 2 plays an important role in predisposing to ALS and that polyQ expansions in ataxin 2 are a significant risk factor for the disease. | polyglutamine | ataxin 2 | Homo sapiens |