Title : Intracerebroventricular administration of morphine confers remote cardioprotection--role of opioid receptors and calmodulin.

Pub. Date : 2011 Apr 10

PMID : 21291882






3 Functional Relationships(s)
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1 Furthermore, remote preconditioning by intracerebroventricular morphine increased the expression of CaM in the hippocampus and the plasma level of calcitonin gene-related peptide (CGRP). Morphine calcitonin-related polypeptide alpha Rattus norvegicus
2 Furthermore, remote preconditioning by intracerebroventricular morphine increased the expression of CaM in the hippocampus and the plasma level of calcitonin gene-related peptide (CGRP). Morphine calcitonin-related polypeptide alpha Rattus norvegicus
3 The results of the present study provide evidence that the cardioprotection of remote preconditioning by intracerebroventricular morphine involves not only all three types of opioid receptors in the central nervous system, but also CaM, which releases CGRP, one of the mediators of remote preconditioning. Morphine calcitonin-related polypeptide alpha Rattus norvegicus