Title : Inhibition of checkpoint kinase 1 sensitizes lung cancer brain metastases to radiotherapy.

Pub. Date : 2011 Mar 4

PMID : 21291864






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 AZD7762 increased ATR/ATM-mediated Chk1 phosphorylation and stabilized Cdc25A, suppressed cyclin A expression in lung cancer cell lines. 3-(carbamoylamino)-5-(3-fluorophenyl)-N-(3-piperidyl)thiophene-2-carboxamide ATR serine/threonine kinase Homo sapiens