Title : Elasticity-dependent modulation of TGF-β responses in human trabecular meshwork cells.

Pub. Date : 2011 May 2

PMID : 21282571






2 Functional Relationships(s)
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1 The contribution of non-Smad signaling pathways to TGF-beta-induced alpha-SMA and PAI-1 expression was assessed using the small molecule inhibitors U0126 and LY294002. U 0126 transforming growth factor beta 1 Homo sapiens
2 The MEK-inhibitor U0126 blocked TGF-beta-induced PAI-1 expression, whereas alpha-SMA expression was enhanced. U 0126 transforming growth factor beta 1 Homo sapiens