Pub. Date : 2011 Feb
PMID : 21280190
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tacrolimus, a cornerstone immunosuppressant, is available as a twice-daily formulation (tacrolimus bid). | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 2 | Tacrolimus, a cornerstone immunosuppressant, is available as a twice-daily formulation (tacrolimus bid). | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 3 | Tacrolimus area under the curve (AUC) from 0 to 24 hours (AUC(0-24) ) at equivalent doses was approximately 50% lower for tacrolimus qd than for bid on day 1 (146 versus 264 ng h/mL, respectively), but by day 14 was comparable between treatments (324 and 287 ng h/mL, respectively) with higher tacrolimus qd doses. | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 4 | There was a strong correlation between AUC(0-24) and concentration at 24 hours for tacrolimus qd and bid (r = 0.92 and r = 0.76, respectively). | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |