Title : Metals affect the structure and activity of human plasminogen activator inhibitor-1. II. Binding affinity and conformational changes.

Pub. Date : 2011 Feb

PMID : 21280128






1 Functional Relationships(s)
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1 Changes in the observed rate constants with varying concentrations of metal allowed accurate determination of binding affinities for cobalt, nickel, and copper, yielding dissociation constants of ~40, 30, and 0.09 muM, respectively. Nickel latexin Homo sapiens