Title : Regional distribution of drug-metabolizing enzyme activities in the liver and small intestine of cynomolgus monkeys.

Pub. Date : 2011 Jun

PMID : 21273732






1 Functional Relationships(s)
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1 This includes midazolam 1"-hydroxylation and testosterone 6beta-hydroxylation, which are catalyzed by cynomolgus monkey cytochrome P450 (CYP) 3A4/5, orthologs of human CYP3A4/5, which are important drug-metabolizing enzymes. testosterone 6beta cytochrome P450 family 3 subfamily A member 4 Homo sapiens