Title : Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.

Pub. Date : 2011 Feb

PMID : 21268072






2 Functional Relationships(s)
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1 Furthermore, inhibition of proteasome activity by MG132 blocked GA-induced down-regulation of mutant p53, causing mutant p53 accumulation in detergent-insoluble cellular fractions. benzyloxycarbonylleucyl-leucyl-leucine aldehyde tumor protein p53 Homo sapiens
2 Furthermore, inhibition of proteasome activity by MG132 blocked GA-induced down-regulation of mutant p53, causing mutant p53 accumulation in detergent-insoluble cellular fractions. benzyloxycarbonylleucyl-leucyl-leucine aldehyde tumor protein p53 Homo sapiens