Title : Defibrotide, by enhancing prostacyclin generation, prevents endothelin-1 induced contraction in human saphenous veins.

Pub. Date : 1990 Oct

PMID : 2126384






1 Functional Relationships(s)
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Protein Name
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1 Defibrotide (200 ug/ml), by releasing 6-keto-PGF 1 alpha, and other vasoactive prostaglandins, antagonized the contractile effect ET-1 (20 ng) in HSV. Prostaglandins endothelin 1 Homo sapiens