Title : Ixabepilone, a novel microtubule-targeting agent for breast cancer, is a substrate for P-glycoprotein (P-gp/MDR1/ABCB1) but not breast cancer resistance protein (BCRP/ABCG2).

Pub. Date : 2011 May

PMID : 21262849






1 Functional Relationships(s)
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1 Overexpression of P-gp also resulted in significantly decreased cell susceptibility to docetaxel, paclitaxel, and vinblastine. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens