Title : CCAAT/ enhancer-binding protein β activation by capsaicin contributes to the regulation of CYP1A1 expression, mediated by the aryl hydrocarbon receptor.

Pub. Date : 2011 Nov

PMID : 21250977






3 Functional Relationships(s)
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1 Treatment with transient receptor potential vanilloid type-1 receptor (TRPV1) or aryl hydrocarbon receptor (AhR) antagonist decreased induction of CYP1A1 expression by capsaicin. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Mus musculus
2 Treatment with transient receptor potential vanilloid type-1 receptor (TRPV1) or aryl hydrocarbon receptor (AhR) antagonist decreased induction of CYP1A1 expression by capsaicin. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Mus musculus
3 Moreover, capsaicin increased Ca(2+) /calmodulin (CaM)-dependent protein kinase (CaMK) and CCAAT/ enhancer-binding protein beta (C/EBPbeta) activation, downstream of TRPV1 receptors. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Mus musculus