Title : Sphingosine potentiates IL-1-mediated prostaglandin E2 production in human fibroblasts.

Pub. Date : 1990 Dec 15

PMID : 2124239






1 Functional Relationships(s)
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1 To examine the role of protein kinase C (PKC) in IL-1-mediated PGE2 production, we treated cells with PMA, which stimulated PGE2 production suggesting a positive role for PKC activation in the regulation of PGE2 synthesis. Tetradecanoylphorbol Acetate interleukin 1 alpha Homo sapiens