Title : Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma.

Pub. Date : 2011 Mar

PMID : 21241278






1 Functional Relationships(s)
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1 We therefore sought to determine whether the IL-6-neutralizing monoclonal antibody siltuximab, formerly CNTO 328, could enhance the activity of melphalan, and to examine some of the mechanisms underlying this interaction. Melphalan interleukin 6 Homo sapiens