Title : Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.

Pub. Date : 2011 Feb 8

PMID : 21222484






1 Functional Relationships(s)
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1 Surprisingly, even though UNG is the only DNA glycosylase in DT40 cells that can act on U A base pairs derived from dUTP incorporation, an isogenic ung(-/-) DT40 cell line showed little change in its sensitivity to RTX as compared to control cells. resiniferatoxin uracil DNA glycosylase Gallus gallus