Title : Nickel(II) chelatase variants directly evolved from murine ferrochelatase: porphyrin distortion and kinetic mechanism.

Pub. Date : 2011 Mar 8

PMID : 21222436






2 Functional Relationships(s)
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Protein Name
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1 The heme biosynthetic pathway culminates with the ferrochelatase-catalyzed ferrous iron chelation into protoporphyrin IX to form protoheme. protoporphyrin IX ferrochelatase Mus musculus
2 The results lead us to propose that the decrease in the induced protoporphyrin IX saddling mode is associated with a less stringent metal ion preference by ferrochelatase and a slower porphyrin chelation step. protoporphyrin IX ferrochelatase Mus musculus