Pub. Date : 2011 Jun
PMID : 21221803
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sivelestat suppresses iNOS gene expression in proinflammatory cytokine-stimulated hepatocytes. | sivelestat | nitric oxide synthase 2 | Rattus norvegicus |
| 2 | We hypothesized that inhibition of iNOS induction underlies the protective effects of sivelestat on the liver. | sivelestat | nitric oxide synthase 2 | Rattus norvegicus |
| 3 | The objective of this study was to investigate whether sivelestat directly influences iNOS induction in cultured hepatocytes, which is used as a simple in vitro injury model, and to determine the mechanism involved. | sivelestat | nitric oxide synthase 2 | Rattus norvegicus |
| 4 | Sivelestat may provide useful therapeutic effects through the suppression of iNOS induction involved in liver injury. | sivelestat | nitric oxide synthase 2 | Rattus norvegicus |