Title : Expression of retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin A.

Pub. Date : 2011 Feb 15

PMID : 21220692






2 Functional Relationships(s)
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1 Remarkably, RA itself could directly induce RALDH2 in both DCs and stromal cells in vitro. Tretinoin aldehyde dehydrogenase family 1, subfamily A2 Mus musculus
2 Furthermore, upon provision of a vitamin A-deficient diet, it was found that RA-mediated signaling was strongly reduced within the small intestines, while RALDH2 mRNA and RALDH enzyme activity in lamina propria DCs and MLN-DCs, as well as RALDH2 mRNA expression in MLN stromal cells, were strongly diminished. Tretinoin aldehyde dehydrogenase family 1, subfamily A2 Mus musculus