Title : Antiepileptic drugs, sex hormones, and PCOS.

Pub. Date : 2011 Feb

PMID : 21204821






1 Functional Relationships(s)
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1 The use of the liver enzyme-inducing AEDs--such as phenobarbital, phenytoin, and carbamazepine--can increase serum sex hormone-binding globulin concentrations, leading to diminished bioactivity of testosterone (T) and estradiol. Phenobarbital sex hormone binding globulin Homo sapiens