Title : Secondary storage of dermatan sulfate in Sanfilippo disease.

Pub. Date : 2011 Mar 4

PMID : 21193389






2 Functional Relationships(s)
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1 Examination of chondroitin/dermatan sulfate catabolic enzymes showed that heparan sulfate and heparin can inhibit iduronate 2-sulfatase. Dermatan Sulfate iduronate 2-sulfatase Homo sapiens
2 Analysis of the chondroitin/dermatan sulfate fraction by chondroitinase ACII digestion showed dermatan sulfate storage, consistent with inhibition of iduronate 2-sulfatase. Dermatan Sulfate iduronate 2-sulfatase Homo sapiens