Title : The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hypertension.

Pub. Date : 2011 May

PMID : 21193036






1 Functional Relationships(s)
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Protein Name
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1 Cytochrome P450 enzymes play an important role in steroid hormone biosynthesis of the human adrenal gland, e.g., the production of cortisol and aldosterone. Steroids cytochrome P450 family 4 subfamily F member 3 Homo sapiens