Title : Pleiotropic effects of cardioactive glycosides.

Pub. Date : 2011

PMID : 21182478






1 Functional Relationships(s)
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1 Cardioactive glycosides, like digoxin, ouabain and related compounds, are drugs that inhibit Na(+)/K(+)-ATPase and have a strong inotropic effect on heart: they cause the Na(+)/Ca(2+) exchanger to extrude Na+ in exchange with Ca(2+) and therefore increase the [Ca(2+)](i) concentration. Digoxin nascent polypeptide associated complex subunit alpha 2 Homo sapiens