Pub. Date : 2010 Dec
PMID : 21177177
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Gefitinib inhibits alpha-smooth muscle actin expression in mice with bleomycin-induced lung fibrosis]. | Bleomycin | actin alpha 2, smooth muscle, aorta | Mus musculus |
| 2 | OBJECTIVE: To evaluate the effect of epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib, on the expression of alpha-smooth muscle actin (alpha-SMA) in mice with lung fibrosis induced by bleomycin. | Bleomycin | actin alpha 2, smooth muscle, aorta | Mus musculus |
| 3 | OBJECTIVE: To evaluate the effect of epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib, on the expression of alpha-smooth muscle actin (alpha-SMA) in mice with lung fibrosis induced by bleomycin. | Bleomycin | actin alpha 2, smooth muscle, aorta | Mus musculus |
| 4 | The phosphorylation of EGFR in the pulmonary mesenchymal cells and epithelial cells and the expression levels of alpha-SMA mRNA and protein were inhibited by gefitinib treatment in mice with intratracheal administration of bleomycin (P<0.05). | Bleomycin | actin alpha 2, smooth muscle, aorta | Mus musculus |