Title : Non-ATG-initiated translation directed by microsatellite expansions.

Pub. Date : 2011 Jan 4

PMID : 21173221






1 Functional Relationships(s)
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1 Additionally, we show that RAN translation across human spinocerebellar ataxia type 8 (SCA8) and myotonic dystrophy type 1 (DM1) CAG expansion transcripts results in the accumulation of SCA8 polyalanine and DM1 polyglutamine expansion proteins in previously established SCA8 and DM1 mouse models and human tissue. polyglutamine RAN, member RAS oncogene family Homo sapiens