Title : MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

Pub. Date : 2011 Jan

PMID : 21173028






1 Functional Relationships(s)
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1 Altogether, our data uncover a novel mechanism linking MYCN to apoptosis that can be triggered by the p53-reactivating compound Nutlin-3, supporting its use in the most difficult-to-treat subset of neuroblastoma. nutlin 3 tumor protein p53 Homo sapiens