Title : The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3.

Pub. Date : 2010 Dec 14

PMID : 21167755






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 RAUL limited type I IFN production by directly catalyzing lysine 48-linked polyubiquitination of both interferon regulatory factor 7 (IRF7) and IRF3 followed by proteasome-dependent degradation. Lysine interferon alpha 1 Homo sapiens