Title : Curcumin I protects the dopaminergic cell line SH-SY5Y from 6-hydroxydopamine-induced neurotoxicity through attenuation of p53-mediated apoptosis.

Pub. Date : 2011 Feb 11

PMID : 21167259






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Curcumin I protects the dopaminergic cell line SH-SY5Y from 6-hydroxydopamine-induced neurotoxicity through attenuation of p53-mediated apoptosis. Curcumin tumor protein p53 Homo sapiens
2 Taken together, these findings indicate that curcumin I protects dopaminergic neurons from 6-OHDA-induced toxicity via the reduction of ROS production, and subsequent attenuation of p53 phosphorylation and reduction of the Bax/Bcl-2 ratio. Curcumin tumor protein p53 Homo sapiens