Title : The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes.

Pub. Date : 2011 Feb

PMID : 21165548






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1 In the present study, we demonstrate that artemisinin inhibits the secretion and the mRNA levels of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1ss, and IL-6 in a dose-dependent manner in phorbol 12-myristate 13-acetate (PMA)-induced THP-1 human monocytes. Tetradecanoylphorbol Acetate interleukin 6 Homo sapiens