Title : [Significance of calcineurin activation and CD40L expression in patients with active lupus nephritis].

Pub. Date : 2005 Aug

PMID : 21162213






2 Functional Relationships(s)
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1 (3) FK506 reduced significantly production of CD40L in spontaneous and PMA/Ionomycin-induced PBMC of LN. Tacrolimus CD40 ligand Homo sapiens
2 Through inhibiting CaN activity, FK506 may prevent abnormal activation of CD40-CD40L costimulatory pathway in lupus nephritis. Tacrolimus CD40 ligand Homo sapiens