Title : Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1.

Pub. Date : 2011 Feb 18

PMID : 21159775






1 Functional Relationships(s)
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1 Mitochondrial cytochrome P450 11A1 (CYP11A1 or P450 11A1) is the only known enzyme that cleaves the side chain of cholesterol, yielding pregnenolone, the precursor of all steroid hormones. Pregnenolone cytochrome P450 family 11 subfamily A member 1 Homo sapiens