Title : [The chronic effect of palmitic acid on apoptosis of pancreatic islet beta-cells and the mechanism].

Pub. Date : 2009 Nov

PMID : 21158056






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RESULTS: Chronic PA dose-dependently (1) decreased the availability and increased the apoptosis of MIN6 cells; (2) decreased the phosphorylation of Akt and Bcl-2, but had no significant effects on Akt and Bax. Palmitic Acid thymoma viral proto-oncogene 1 Mus musculus
2 RESULTS: Chronic PA dose-dependently (1) decreased the availability and increased the apoptosis of MIN6 cells; (2) decreased the phosphorylation of Akt and Bcl-2, but had no significant effects on Akt and Bax. Palmitic Acid thymoma viral proto-oncogene 1 Mus musculus
3 CONCLUSION: Chronic PA dose-dependently induced apoptosis of MIN6 cells, and this effect was possibly regulated by Akt/Bcl-2. Palmitic Acid thymoma viral proto-oncogene 1 Mus musculus