Title : Angiogenic effect of laminin involves modulation of cyclooxygenase-2 and prostaglandin levels.

Pub. Date : 2011 Jan

PMID : 21148739






1 Functional Relationships(s)
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1 Use of pharmacological inhibitors suggested that the modulation in the expression of COX-2 and thereby the levels of PGE(2) and PGD(2) in endothelial cells by Ln is mediated through the alpha(6)beta(4) integrin-p38MAPK (mitogen-activated protein kinase)-NF-kappaB signaling pathway. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens