Title : Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation.

Pub. Date : 2011 Feb 25

PMID : 21147093






1 Functional Relationships(s)
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1 LPS-induced phosphorylation of IkappaBalpha and p38 MAPK was blocked by Biochanin-A and it inhibited IL-6, IL-1beta and TNF-alpha production in RAW264.7 cells indicating its anti-inflammatory activity in association with anti-proliferation. lps interleukin 1 beta Mus musculus