Pub. Date : 2011 Feb
PMID : 21132465
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sca-1(+)HSC induced aging by tert-butylhydroperoxide (t-BHP, final concentration of 100 mumol/L) for 6 h to establish the murine HSC aging model in vitro. | tert-Butylhydroperoxide | ataxin 1 | Mus musculus |
| 2 | Sca-1(+)HSC induced aging by tert-butylhydroperoxide (t-BHP, final concentration of 100 mumol/L) for 6 h to establish the murine HSC aging model in vitro. | tert-Butylhydroperoxide | ataxin 1 | Mus musculus |
| 3 | After 6 h cocultured with 100 mumol/L t-BHP, the ability of aging Sca-1(+) HSC to form mixed hematopoietic progenitor colony, self-renewal and multi-differentiation were decreased significantly. | tert-Butylhydroperoxide | ataxin 1 | Mus musculus |
| 4 | The t-BHP can induce Sca-1(+) HSC senescence in vitro. | tert-Butylhydroperoxide | ataxin 1 | Mus musculus |
| 5 | The signal transduction pathways of p16(INK4a)-retinoblastoma and P19(Arf)-Mdm2-P53-P21(Cip1/Waf1) may play key roles in the Sca-1(+) HSC senescence induced by t-BHP. | tert-Butylhydroperoxide | ataxin 1 | Mus musculus |