Title : Phenotypic enhancement of thymidylate synthetase pathway inhibitors following ablation of Neil1 DNA glycosylase/lyase.

Pub. Date : 2010 Dec 15

PMID : 21131780






1 Functional Relationships(s)
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1 Inhibition of thymidylate synthetase (TS) leads to a decrease in cellular TTP levels, replication stress and increased genomic incorporation of uridine (dUMP). 2'-deoxyuridylic acid thymidylate synthetase Homo sapiens