Title : TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells.

Pub. Date : 2011 Feb

PMID : 21131394






2 Functional Relationships(s)
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1 The changes in oxidant/antioxidant enzymes and IL-6 release were reversed by the antioxidants N-acetyl-cysteine (NAC) and ebselen through inhibition of Smad3 phosphorylation, indicating redox-dependent activation of Smad3 by TGF-beta. Acetylcysteine interleukin 6 Homo sapiens
2 The changes in oxidant/antioxidant enzymes and IL-6 release were reversed by the antioxidants N-acetyl-cysteine (NAC) and ebselen through inhibition of Smad3 phosphorylation, indicating redox-dependent activation of Smad3 by TGF-beta. Acetylcysteine interleukin 6 Homo sapiens