Pub. Date : 2011 Feb
PMID : 21127283
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Combined catechol-O-methyltransferase and mu-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects. | Morphine | catechol-O-methyltransferase | Homo sapiens |
2 | In this study, we investigated whether combined catechol-O-methyltransferase and mu-opioid receptor polymorphisms contribute to the morphine response in postoperative analgesia. | Morphine | catechol-O-methyltransferase | Homo sapiens |
3 | RESULTS: The heterozygous patients with mu-opioid receptor A118G and catechol-O-methyltransferase G1947A mutation consumed significantly less morphine in the postanesthetic recovery room and 48 hours after surgery compared with homozygous patients of the A118 variant. | Morphine | catechol-O-methyltransferase | Homo sapiens |