Title : Pharmacological targeting of β-adrenergic receptor functions abrogates NF-κB signaling and MMP-9 secretion in medulloblastoma cells.

Pub. Date : 2010 Nov 15

PMID : 21124749






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Propranolol inhibition of IkappaB phosphorylation was shown to occur with optimal efficacy at 30 muM. Propranolol latexin Homo sapiens
2 Although propranolol, at up to 100 muM, did not affect cell viability, it potentiated PMA- mediated signaling that ultimately led to diminished phosphorylation of Akt. Propranolol latexin Homo sapiens