Title : A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells.

Pub. Date : 2011 Jun

PMID : 21120637






2 Functional Relationships(s)
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1 Remarkably, the synergistic effect of 8-Br-cAMP and VPA on cellular reprogramming may be due to the transient decrease of p53 protein during the early stages of reprogramming. 8-Bromo Cyclic Adenosine Monophosphate tumor protein p53 Homo sapiens
2 In addition, 8-Br-cAMP and VPA have a synergistic effect on cellular reprogramming, which may be in part due to the transient down-regulation of the p53 signaling pathway during the early stages of reprogramming. 8-Bromo Cyclic Adenosine Monophosphate tumor protein p53 Homo sapiens