Pub. Date : 2011 Oct
PMID : 21118718
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This phenotypic difference in the proliferative response to cAMP appears to involve cross-talk between cAMP and Ca(2+) signaling to B-Raf, a kinase upstream of the MEK/ERK pathway. | Cyclic AMP | mitogen-activated protein kinase 1 | Homo sapiens |
2 | This phenotypic difference in the proliferative response to cAMP appears to involve cross-talk between cAMP and Ca(2+) signaling to B-Raf, a kinase upstream of the MEK/ERK pathway. | Cyclic AMP | mitogen-activated protein kinase 1 | Homo sapiens |
3 | In normal cells, B-Raf is repressed by Akt (protein kinase B), a Ca(2+)-dependent kinase, preventing cAMP activation of ERK and cell proliferation. | Cyclic AMP | mitogen-activated protein kinase 1 | Homo sapiens |