Title : Binding of ATP to eukaryotic initiation factor 2. Differential modulation of mRNA-binding activity and GTP-dependent binding of methionyl-tRNAMetf.

Pub. Date : 1990 Jun 5

PMID : 2111815






1 Functional Relationships(s)
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1 Hydrolysis of ATP is not required for inhibition, for adenyl-5"-yl imidodiphosphate (AMP-PNP), a nonhydrolyzable analogue of ATP, is as active an inhibitor; adenosine 5"-O-(thiotriphosphate) (ATP gamma S) inhibits far more weakly. Adenylyl Imidodiphosphate purine nucleoside phosphorylase Homo sapiens