Title : Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.

Pub. Date : 2011 Feb 27

PMID : 21115097






1 Functional Relationships(s)
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1 Although all of the pyrethroids and most of the organochlorines and acid amides acted as PXR agonists, a wide range of pesticides with diverse structures also showed hPXR and/or mPXR agonistic activity. Pyrethrins nuclear receptor subfamily 1 group I member 2 Homo sapiens